Trans-Arterial Chemo Embolisation (DC Bead) of a Diffuse or Multifoca Hepatoma
Jakub Wiskirchen, MD, Gunnar Tepe, MD, and Philippe L. Pereira, MD
Department for Diagnostic and Interventional Radiology University Hospital Tübingen, Germany
Patient History
Male patient (66 y, HCV positive) suffering from an ill defined, multifocal HCC with tumour nodules mainly in the right lobe but also (to a smaller degree) in the left lobe. CT scans (Figs 1 and 2) showed a mainly hypervascular, multinodular HCC with some necrosis (Fig 2).
An angiography performed with a 4Fr C2 Cobra™ (Cook®) catheter placed in the main hepatic artery confirmed the diagnosis of a large, multinodular HCC (Fig 3).
Procedure
Using a 2.7Fr microcatheter (Progreat™, Terumo®) the feeder of the tumour in the right lobe was intubated (Fig 4) and the tumour was embolised with a total of 4ml DC Bead™ (Biocompatibles) loaded with 100mg epirubicin (Pfizer)
Outcome
The control angiography confirmed the vascular denudation of the tumour nodules in the right hepatic lobe (Fig 5). The nodules in the left lobe were not treated at this time to prevent too much stress on liver function in one session. A control CT scan obtained one day after the embolisation confirmed the vascular denudation of the tumour. The air bubbles within the tumour are a regular finding following DC Bead™ embolisation.
DC Bead Sizes and Label Colours
| Bead size & label colour | Volume of beads |
Product code | Time to >90% loading | Time to 98% loading |
|---|---|---|---|---|
| 100-300µm | 2ml | DC2V103 | 5 mins | 20 mins |
| 300-500µm | 2ml | DC2V305 | 10 mins | 40 mins |
| 500-700µm | 2ml | DC2V507 | 20 mins | 75 mins |
| 700-900µm | 2ml | DC2V709 | 30 mins | 100 mins |
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Disclaimer
The products may not be available for sale, may not be registered, approved or cleared for use as claimed, in all countries where Biocompatibles is represented.